43 research outputs found
Conceptual Discovery of Educational Resources through Learning Objectives
Get PDFΠεριέχει το πλήρες κείμενοThis poster reports on current work with the NSF-funded Achievement
Standards Network (ASN) to support discovery of educational resources
in digital libraries using conceptual graphs of officially promulgated achievement
standards statements. Conceptual graphs or knowledge maps of achievement
standards reveal the macrostructure of the learning domain modeled by
those standards and support higher-level understanding by teachers and students.
The work builds on the conceptual framework of the AAAS knowledge
maps by providing the means to flexibly define and deploy new relationship
schemas to fit the disparate modeling needs of the nearly 740 learning standards
documents in the ASN repository. Using an RDF-based, node-link representation
of learning goals and the relationships among them, the ASN Knowledge
Map Service will provide the framework to correlate educational resources to
nodes in conceptual models in order to augment more conventional mechanisms
of discovery and retrieval in digital libraries
Stochastic B-series analysis of iterated Taylor methods
Full text linkFor stochastic implicit Taylor methods that use an iterative scheme to
compute their numerical solution, stochastic B--series and corresponding growth
functions are constructed. From these, convergence results based on the order
of the underlying Taylor method, the choice of the iteration method, the
predictor and the number of iterations, for It\^o and Stratonovich SDEs, and
for weak as well as strong convergence are derived. As special case, also the
application of Taylor methods to ODEs is considered. The theory is supported by
numerical experiments
Pegfilgrastim Vs Filgrastim-Based Steady State Autologous HSC Mobilization in the Setting of Patient Adapted (“Just in Time”) Plerixafor: Efficacy and Economic Outcomes
Get PDF
Early in-hospital exposure to statins and outcome after intracerebral haemorrhage - Results from the Virtual International Stroke Trials Archive
Get PDFIntroduction Recent data suggest that statin use after intracerebral haemorrhage might be beneficial. However, data on the effects of early in-hospital statin exposure are lacking. Therefore, we sought to assess whether (1) early statin exposure during the acute phase after intracerebral haemorrhage and (2) early continuation of prevalent statin use are associated with favourable functional outcome. Patients and methods Data were obtained from the Virtual International Stroke Trials Archive. Patients were categorised according to use patterns of statins during this early in-hospital phase (continuation, discontinuation or new initiation of statins). Univariate and multivariable analyses were conducted to explore the association between early statin exposure and functional outcome. Results A total of 919 patients were included in the analysis. Early in-hospital statin exposure (n = 89, 9.7%) was associated with better functional outcome (modified Rankin Scale <= 3) compared with 790 patients without statin exposure before or early after the event (66% versus 47%, adjusted OR 2.1, 95% confidence interval 1.3-3.6). Compared with patients without exposure to statins before and early after the event, early continuation of statin therapy (n = 57) was associated with favourable functional outcome (adjusted odds ratio 2.6, 95% confidence interval 1.3-5.2). The association between early continuation of statins and outcome remained robust in sensitivity analyses restricted to patients able to take oral medication within 72 h and one-week survivors. Discussion It is possible that part of the observed associations are not due to a protective effect of statins but are confounded by indication bias. Conclusion Statin exposure and continuation of prevalent statin therapy early after intracerebral haemorrhage are associated with favourable functional outcome after 90 days
