267 research outputs found
The critical Ising lines of the d=2 Ashkin-Teller model
The universal critical point ratio is exploited to determine positions of
the critical Ising transition lines on the phase diagram of the Ashkin-Teller
(AT) model on the square lattice. A leading-order expansion of the ratio in
the presence of a non-vanishing thermal field is found from finite-size scaling
and the corresponding expression is fitted to the accurate perturbative
transfer-matrix data calculations for the square clusters with
.Comment: RevTex, 4 pages, two figure
Exact relations between damage spreading and thermodynamic functions for the N-color Ashkin-Teller model
Exact results are derived relating quantities computable by the so-called
damage spreading method and thermodynamic functions for the N-color
Ashkin-Teller model. The results are valid for any ergodic dynamics. Since we
restrict our analysis to the ferromagnetic case the results are also valid for
any translational invariant lattice. The derived relations should be used in
order to determine numerically the N-color Ashkin-Teller critical exponents
with better accuracy and less computational efforts than standard Monte Carlo
simulations.Comment: 6 pages, to be published in JSTAT (Journal of Statistical Mechanics:
Theory and Experiment). The results of a computer simulation were included
for N=3 as an example on how to use the analytical relations derived in the
paper as a guide to obtain the critical temperature and critical exponent
Scalar meson production in nucleon-nucleon collisions near threshold
We establish the model-independent spin structure of the matrix elements for
the near-threshold scalar meson production in and -collisions, when
the final particles are emitted in S-state. Polarization phenomena are derived
in a general form. The properties of the channel dynamics, which is based
on different meson exchanges, are studied in terms of the channel
parametrization of the matrix element. The prediction of a 'realistic' model,
based on -exchanges are also presented.Comment: 16 pages 6 figure
Relativistic Effects in the Scalar Meson Dynamics
A separable potential formalism is used to describe the and
interactions in the scalar-isoscalar states in the energy range
from the threshold up to 1.4 GeV. Introduction of relativistic
propagators into a system of Lippmann-Schwinger equations leads to a very good
description of the data ( per one degree of freedom). Three
poles are found in this energy region: fo(500) ( MeV,
MeV), fo(975) ( MeV, MeV) and
fo(1400) ( MeV, MeV). The fo(975) state can be
interpreted as a bound state. The fo(500) state may be
associated with the often postulated very broad scalar resonance under the
threshold (sometimes called or meson). The
scattering lengths in the and channels have also been
obtained. The relativistic approach provides qualitatively new results (e.g.
the appearance of the fo(500)) in comparison with previously used
nonrelativistic approach.Comment: 30 pages in LaTeX + 5 figures available on request. Preprint Orsay No
IPNO/TH 93-3
LaAlO3 stoichiometry found key to electron liquid formation at LaAlO3/SrTiO3 interfaces
Emergent phenomena, including superconductivity and magnetism, found in the
two-dimensional electron liquid (2-DEL) at the interface between the insulators
LaAlO3 and SrTiO3 distinguish this rich system from conventional
two-dimensional electron gases at compound semiconductor interfaces. The origin
of this 2-DEL, however, is highly debated with focus on the role of defects in
the SrTiO3 while the LaAlO3 has been assumed perfect. Our experiments and first
principles calculations show that the cation stoichiometry of the nominal
LaAlO3 layer is key to 2-DEL formation: only Al-rich LaAlO3 results in a 2-DEL.
While extrinsic defects including oxygen deficiency are known to render
LaAlO3/SrTiO3 samples conducting, our results show that in the absence of such
extrinsic defects, an interface 2-DEL can form. Its origin is consistent with
an intrinsic electronic reconstruction occurring to counteract a polarization
catastrophe. This work provides a roadmap for identifying other interfaces
where emergent behaviors await discovery
Australian Gay Men’s Satisfaction with Sexual Agreements: The Roles of Relationship Quality, Jealousy, and Monogamy Attitudes
Wet Adhesion and Adhesive Locomotion of Snails on Anti-Adhesive Non-Wetting Surfaces
Creating surfaces capable of resisting liquid-mediated adhesion is extremely difficult due to the strong capillary forces that exist between surfaces. Land snails use this to adhere to and traverse across almost any type of solid surface of any orientation (horizontal, vertical or inverted), texture (smooth, rough or granular) or wetting property (hydrophilic or hydrophobic) via a layer of mucus. However, the wetting properties that enable snails to generate strong temporary attachment and the effectiveness of this adhesive locomotion on modern super-slippy superhydrophobic surfaces are unclear. Here we report that snail adhesion overcomes a wide range of these microscale and nanoscale topographically structured non-stick surfaces. For the one surface which we found to be snail resistant, we show that the effect is correlated with the wetting response of the surface to a weak surfactant. Our results elucidate some critical wetting factors for the design of anti-adhesive and bio-adhesion resistant surfaces
DGCR8 HITS-CLIP reveals novel functions for the Microprocessor
The Drosha-DGCR8 complex (Microprocessor) is required for microRNA (miRNA) biogenesis. DGCR8 recognizes the RNA substrate, whereas Drosha functions as the endonuclease. High-throughput sequencing and crosslinking immunoprecipitation (HITS-CLIP) was used to identify RNA targets of DGCR8 in human cells. Unexpectedly, miRNAs were not the most abundant targets. DGCR8-bound RNAs also comprised several hundred mRNAs as well as snoRNAs and long non-coding RNAs. We found that the Microprocessor controls the abundance of several mRNAs as well as of MALAT-1. By contrast, DGCR8-mediated cleavage of snoRNAs is independent of Drosha, suggesting the involvement of DGCR8 in cellular complexes with other endonucleases. Interestingly, binding of DGCR8 to cassette exons, acts as a novel mechanism to regulate the relative abundance of alternatively spliced isoforms. Collectively, these data provide new insights in the complex role of DGCR8 in controlling the fate of several classes of RNAs
Programmed death ligand-1 expression on donor T cells drives graft-versus-host disease lethality.
Programmed death ligand-1 (PD-L1) interaction with PD-1 induces T cell exhaustion and is a therapeutic target to enhance immune responses against cancer and chronic infections. In murine bone marrow transplant models, PD-L1 expression on host target tissues reduces the incidence of graft-versus-host disease (GVHD). PD-L1 is also expressed on T cells; however, it is unclear whether PD-L1 on this population influences immune function. Here, we examined the effects of PD-L1 modulation of T cell function in GVHD. In patients with severe GVHD, PD-L1 expression was increased on donor T cells. Compared with mice that received WT T cells, GVHD was reduced in animals that received T cells from Pdl1-/- donors. PD-L1-deficient T cells had reduced expression of gut homing receptors, diminished production of inflammatory cytokines, and enhanced rates of apoptosis. Moreover, multiple bioenergetic pathways, including aerobic glycolysis, oxidative phosphorylation, and fatty acid metabolism, were also reduced in T cells lacking PD-L1. Finally, the reduction of acute GVHD lethality in mice that received Pdl1-/- donor cells did not affect graft-versus-leukemia responses. These data demonstrate that PD-L1 selectively enhances T cell-mediated immune responses, suggesting a context-dependent function of the PD-1/PD-L1 axis, and suggest selective inhibition of PD-L1 on donor T cells as a potential strategy to prevent or ameliorate GVHD
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