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Interactions between nutritional programming, genotype, and gut microbiota in Atlantic salmon: Long-term effects on gut microbiota, fish growth and feed efficiency
Get PDFNutritional programming (NP) is a tool for developing adaptive changes that can be expressed in adulthood by exposing individuals to a stimulus early in life. This study investigated the interactions between nutritional programming (NP), genotype and gut microbiota in Atlantic salmon (Salmo salar) across the life cycle, to potentially improve feed efficiency and fish health. Approximately 5100 eggs from six families characterised by high (HP) or low pigment retention (LP) were incubated and divided into four groups (HPM, HPV, LPM, LPV) that received a stimulus diet based on marine (M) (61 % fishmeal and 8 % fish oil) or vegetable (V) (5 % fishmeal, plant proteins and rapeseed oil) ingredients. This stimulus phase lasted three weeks, followed by a 49-week freshwater intermediate phase with fish fed a commercial feed subsequent to seawater transfer. In seawater, the fish were initially fed a commercial feed for 13 weeks and then switched to a plant-based “challenge” diet with approximately 3 % EPA + DHA until the end of the experiment, at 101 weeks, at which point fish were 4 kg. During the study, survival rates, SGR, and FCR were monitored. Samples for microbiota analysis were collected at T0 (after the stimulus), T1 (before the challenge), T2 (challenge, after the feed change), and T3 (end of the feeding trial). Gut and feed microbiota were analysed by bacterial DNA extraction, Illumina NGS library preparation and raw sequencing data analysis using QIIME 2 and PICRUSt software. Gut microbiota composition changed with fish age, independent of NP and pigmentation genotype, emphasising the importance of developmental stage. Early diet influenced beta diversity and increased the number of specific bacteria, but these changes decreased with time. NP influenced the gut microbiota during the stimulus phase but not during the challenge phase, showing that the current diet has a greater influence than the earlier diet. Some microbial genera were associated with different genotypes and diets, suggesting interactions between genotype and stimulus diet. Differences in the metabolic potential of the gut microbiota due to the stimulus diet were observed but were not associated with differences in growth and feed utilisation. The study concludes that early nutritional programming with a plant-based diet has a transient effect on growth and gut microbiota, with long-term growth performance being more strongly influenced by pigmentation genotype. Further studies on the interactions between genotype, diet and microbiota are required
Making and Unmaking the Cold War in Museums
Get PDFTo introduce “Cold War Museology” and a volume of new essays in this chapter, we develop what we propose to be core themes of the subject. Our aim is to establish the Cold War as a key topic in museum studies, both in its own right, but also in terms of how it speaks to more general themes of contemporary museology. In doing so, we seek to learn from Cold War critical heritage research, bringing some of its analytical rigour to bear on museum work. Focusing primarily on curatorial practices and display analysis, we highlight three key themes for further discussion: the way in which objects reflect broader networks; the relationship between spaces, places and things (and specifically the ways in which objects create meanings when they are removed from their original locations); and the values that attach to collections. We also highlight absences in our discussions, including the question of how to address the global nature of the Cold War in the context of debates about decolonising collections as well as questions of gender and race when they appear to be absent from collections relating to the Cold War. This volume calls for a museology that reflects the ways in which the Cold War was both made and unmade, the spaces and places where this happens and what this means for museum collections, interpretation and engagement
The Pain of Thinking at Light Speed: Posthuman Play as Response to “I Have No Mouth, and I Must Scream"
No full textSearching for solutions to the coming extinction brought on by the anthropocene, some turn their attention to increasingly powerful computation. Billionaires, transhumanists but also James Lovelock write of technological salvation as a solution to climate destruction. In contrast to this, apocalyptic science fiction warns against placing too much faith in supercomputers. Harlan Ellison’s short story “I have no Mouth and I Must Scream” serves as a starting point for discussing digital technologies in and after the Anthropocene. I suggest – with reference to both Ellison’s short story and the videogame inspired by it – that supercomputation is unlikely to be a viable solution to humanity’s extinction. Thinking as a supercomputer, looking for answers at light speed, the solution would emerge, as in Ellison’s work, that humanity is already doomed. Instead, embracing a rejection of standard of duration and experience, I champion an emphasis on the possibility, necessity, and unique power of play and making ‘odd kin’ in the face of a computationally unavoidable Armageddon
Understanding Curriculum Making by teachers: implications for policy as text and as practice
Get PDFRecent debates in curriculum studies have focused on the role of teachers as active curriculum makers. In this chapter, we argue for a more systemic approach to curriculum making as social practice. Our particular focus is on micro and nano curriculum making by teachers, that is curriculum making in schools and classrooms respectively, as curricular programmes are developed and enacted into practice. In making sense of these complex practices, we draw upon a theoretical typology for understanding and analysing curriculum making across different sites within education systems, and an ecological understanding of teacher agency. We apply these theoretical insights to the analysis of various influences on micro/nano curriculum, emerging from a range of recent empirical studies in five European education systems. In undertaking this analysis, we challenge prevalent notions of curriculum making as a linear process of delivery or implementation, instead seeking to understand it as interpretation and enactment across sites by multiple social actors, and tracing the multiple and dynamic connection
"Addressing the Non-Communicable Diseases (NCDs) burden and protecting the young through comprehensive Alcohol Policies: Lessons from recent studies in Africa".
No full textThe age-standardized alcohol-attributable burden of disease and injury is highest in the WHO African Region, at 70.6 deaths and 3 044 DALYs per 100 000 people, placing an enormous strain on already challenged health systems. Drinkers in Africa consume 21% more alcohol per day than the global average. Small disposable plastic sachets- pouches which contain single use quantities of alcohol which often contain 40% spirits- have led to significant abuse amongst the most vulnerable and poorest communities in Malawi and Uganda. Concerns about harmful consumption and the public health and societal impact led to national bans on sachets of alcohol in Malawi (2016) and Uganda (2019), but those may not have had the impact anticipated. We will conduct interviews with key policy stakeholders and with district and local stakeholders in enforcement and trade in Malawi and Uganda to understand the adoption and formulation of the bans, what mechanisms for implementation were proposed and put in place, how the bans were enforced in practice, and any unintended consequences that have resulted. We will conduct focus group discussions with community members, health staff from local health centres and with traditional/ church leaders and school headteachers to explore the perceived impact of the ban and any unintended consequences from a local community perspective. Our multidisciplinary international team will conduct a robust analysis based the Health Policy Analysis framework to highlight contextual factors important for the transferability of findings to other Sub-Saharan countries in order to inform alcohol policy development and implementation across the region. We will publish results in peer reviewed journals and share them at stakeholder events in each country to discuss how the results may be used to further regulation of the supply of alcohol and reduction of related harms. Our researchers in LMICs will benefit from a strong capacity-building and research skills programme
Different coasts for different folks: Place-based community values and experience mediate social acceptability of low-trophic aquaculture
Get PDFThe expansion of low-trophic aquaculture (shellfish and sea plants) is limited in many regions by a fragmented regulatory process that is difficult for smallholder farmers to navigate. Small-scale Aquaculture Development Areas (ADAs) can remove some of this regulatory burden by establishing pre-approved zones for aquaculture development; however, an understanding of local support for low-trophic aquaculture is needed to understand the potential of ADAs. A survey was used to solicit information about community support for shellfish and sea plant aquaculture in Pictou County, a coastal area of Nova Scotia, Canada. Participants had a positive impression of low-trophic aquaculture, but residents in one coastal area reported greater perceived negative impacts on the recreational use and enjoyment of coastal areas and views, while residents in another coastal area reported a higher level of support for shellfish aquaculture. In general, participants also valued community involvement in aquaculture management, local ownership of farms, and community benefits from the presence of farms. Results suggest that top-down communication is unlikely to play a significant role in acceptability. Instead, experience of low trophic aquaculture and place-based values are important for understanding social acceptability. Community involvement in the development of ADAs and the distribution of benefits from farming could support trust in ADAs and social licence for low-trophic aquaculture
Mobilising Care for Cultural Heritage in Russia’s War Against Ukraine.
No full textThis report provides an overview of key transnational networks, trends and challenges in the provision of care for cultural heritage in Ukraine between the 2022 Russian full-scale invasion and February 2025. Approaches to heritage protection in war have developed considerably over the last 20 years, as have the range of actors involved, extending beyond state administration and public bodies to diverse INGOs and NGOs. However, the complex networks and political economies involved in this crowded landscape are not well understood. It is increasingly recognised that cultural emergency responses intersect with humanitarian ones, but how this happens in practice is rarely explored. Without this understanding, calls for greater coordination and coherence, as well integration of heritage interventions with humanitarian ones, will be difficult to implement. Our research therefore aims to advance knowledge of how care for cultural heritage in war is mobilised through aid and capacity-building, alongside legal and regulatory frameworks, including civilian support and emergency responses. Based on extensive qualitative social research across Europe, the report identifies the actors, resources and reasoning involved, as well as the financial, political and practical contexts of their operation. We unpick the networks, supply chains and organisational alliances entailed, both inside Ukraine and among Ukraine’s allies, showing what actions are taken, by whom, and with what consequences. We also identify factors that facilitate or hinder how care is delivered in practice, particularly constraints that local professionals might face in their effort to shape the agenda of international support. Our results provide new knowledge about cooperation and collaboration in various phases of the war, and show how cultural heritage emergency response, humanitarian aid, and support for social cohesion and resilience, intersect in practice. Analysing care for cultural heritage in this broader, cross-cutting framework transforms understanding of both the social role of cultural heritage in wartime, and the true extent of the networks and resources involved. The Ukrainian example also powerfully illustrates the relevance of ongoing heritage and memory work in the pre-recovery phase with important wider implications for policy and practice. The overarching objective is to produce more effective and better coordinated support for projects and activities involved in caring for Ukraine’s heritage, and the professionals, activists and lay communities involved in them
Anchoring Museum Objects in the Cold War: The Hidden Meanings of a Transatlantic Telephone Cable
Get PDFThis chapter uses a piece of the first transatlantic telephone cable in the collection of National Museums Scotland to interrogate the ways in which museum objects attain significance as Cold War objects. It highlights the ways in which multiple meanings – and layers of meanings – adhere to objects at the same time. Objects not only connect these meanings, but they also exhibit elements of dissonance, noise and silence. Hence, this chapter explores the potential of the concept of anchoring, developed in the context of the history of science and technology by Christian Götter, for a Cold War museology. It offers a number of conclusions about the meaning of Cold War objects in museum collections, their collection, interpretation and display. By bringing history and museology into conversation with one another, this chapter also highlights the ways in which historians can learn through engaging with museum collections and how, in turn, museum and heritage professionals might benefit from interacting with historical scholarship
Chemistry Education for Climate Empowerment and Action
No full textUrgent action is needed across the world to combat climate change and its impact on the social, economic, and environmental well-being of humans and the planet. This important topic is one that is a priority for integration into chemistry classrooms, laboratories, and outreach efforts. It connects strongly to foundational chemistry concepts and highlights the critical role chemistry will play in finding solutions to the many challenges faced in reducing greenhouse gases due to human activity. This Special Issue presents a broad collection of efforts by chemistry educators across the globe to create innovative ways to motivate and inspire students and preservice teachers with the relevant chemistry knowledge, climate literacy, and scientific responsibility needed for climate action. A range of interactive tools, active-learning methodologies, and interdisciplinary approaches provide a wealth of resources for a broad range of teaching environments and ideas for instructors seeking to incorporate climate education and instill advocacy into chemistry programs
Novel Perspectives on Status in Global Politics
Get PDFThis thematic issue advances debates on status in international relations (IR) by integrating novel empirical research with innovative theoretical perspectives. It moves beyond traditional power‐centric views, highlighting the social and relational dimensions of status‐seeking as a diplomatic and foreign policy practice. The contributions explore, for instance, how states pursue status through cooperation, adherence to international norms, and strategic identity management. By examining diverse cases, including non‐traditional status‐seekers, this collection of contributions underscores the multifaceted nature of status‐seeking, involving both material and ideational factors, and enriches the literature on status in IR, offering new insights into the complex dynamics of international hierarchy and state behaviour. In this editorial, we highlight the main findings and give an outlook on the overarching contribution to IR research
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